The new NFL season kicks off with an intriguing clash at Lucas Oil Stadium, where the Indianapolis Colts host the Miami Dolphins on Sunday, September 7, 2025.

The AFC showdown gets underway at 1:00 pm ET (12:00 pm CT / 10:00 am PT / 6:00 pm BST) and is live on CBS across the United States.

How to Watch Colts vs Dolphins

  • Date: Sunday, September 7, 2025
  • Kick-off Time: 1:00 pm ET / 12:00 pm CT / 10:00 am PT / 6:00 pm BSTTV Channel (US): CB
  • Live Stream (US): Fubo (free trial available)
  • Outside the US: NFL Game Pass via DAZN

Fans can also stream the action via Fubo, while international viewers can tune in on NFL Game Pass through DAZN, which offers over 200 games, NFL RedZone, and full Super Bowl coverage.

For those in the U.S., CBS will carry the broadcast nationwide, providing the first look at two teams desperate to set the right tone in 2025.

Cord cutters won’t miss out either, with Fubo offering live streaming options and free trial access. Internationally, DAZN’s NFL Game Pass continues to be the go-to choice, bringing wall-to-wall coverage of every regular-season and playoff matchup.

From a betting perspective, the Colts are being edged as -1.5 point favourites, with the Over/Under set at 47 points.

The line reflects the uncertainty surrounding Miami’s roster, as both quarterback Tua Tagovailoa and star wideout Tyreek Hill remain questionable to feature. Without them, Miami’s attack risks stalling, as shown last year when the Dolphins dropped four of six games without Tua en route to an 8-9 record.

Indianapolis are hoping a fresh start under Daniel Jones, confirmed as starter ahead of Anthony Richardson, can finally break their streak of mediocrity. The Colts also finished 8-9 in 2024, missing the playoffs after falling to the Giants in Week 17. The franchise has now gone nine straight years without an AFC South crown, and head coach Shane Steichen knows improvement is overdue.

The Dolphins, meanwhile, remain a puzzle. Reports of locker room unrest during training camp have only fuelled concerns, and with Hill’s pace and Tua’s accuracy in doubt, Miami’s offensive identity is under threat. However, if both stars are cleared to play, their ability to stretch the field could quickly shift the balance of Sunday’s contest.

For Colts fans, home advantage will feel crucial. Lucas Oil Stadium will be rocking on opening day, and the defence will look to pile pressure on Miami’s quarterback situation. Jones, making his Indianapolis debut, has an early chance to win over the home crowd and prove he can be a steady hand after the turbulence of recent seasons.

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